The large variety of compute-heavy and data-driven applications accelerate the need for a distributed I/O solution that enables cost-effective scaling of resources between networked hosts. For example, in a cluster system, different machines may have various devices available at different times, but moving workloads to remote units over the network is often costly and introduces large overheads compared to accessing local resources. To facilitate I/O disaggregation and device sharing among hosts connected using Peripheral Component Interconnect Express (PCIe) non-transparent bridges, we present SmartIO. NVMes, GPUs, network adapters, or any other standard PCIe device may be borrowed and accessed directly, as if they were local to the remote machines. We provide capabilities beyond existing disaggregation solutions by combining traditional I/O with distributed shared-memory functionality, allowing devices to become part of the same global address space as cluster applications. Software is entirely removed from the data path, and simultaneous sharing of a device among application processes running on remote hosts is enabled. Our experimental results show that I/O devices can be shared with remote hosts, achieving native PCIe performance. Thus, compared to existing device distribution mechanisms, SmartIO provides more efficient, low-cost resource sharing, increasing the overall system performance

Deep learning-based tools may annotate and interpret medical data more quickly, consistently, and accurately than medical doctors. However, as medical doctors are ultimately responsible for clinical decision-making, any deep learning-based prediction should be accompanied by an explanation that a human can understand. We present an approach called electrocardiogram gradient class activation map (ECGradCAM), which is used to generate attention maps and explain the reasoning behind deep learning-based decision-making in ECG analysis. Attention maps may be used in the clinic to aid diagnosis, discover new medical knowledge, and identify novel features and characteristics of medical tests. In this paper, we showcase how ECGradCAM attention maps can unmask how a novel deep learning model measures both amplitudes and intervals in 12-lead electrocardiograms, and we show an example of how attention maps may be used to develop novel ECG features.

Gastrointestinal endoscopy has been an active field of research motivated by the large number of highly lethal GI cancers. Early GI cancer precursors are often missed during the endoscopic surveillance.   The high missed rate of such abnormalities during endoscopy is thus a  critical bottleneck. Lack of attentiveness due to tiring procedures, and requirement of training are few contributing factors. An automatic  GI  disease classification system can help reduce such risks by flagging suspicious frames and lesions. GI endoscopy consists of several multi-organ surveillance, therefore, there is need to develop methods that can generalize to various endoscopic findings. In this realm, we present a comprehensive analysis of the  Medico  GI  challenges:  Medical  Multimedia Task at MediaEval 2017, Medico Multimedia Task at MediaEval 2018,  and  BioMedia  ACM  MM  Grand  Challenge  2019.  These challenges are initiative to set-up  a  benchmark for different computer vision methods applied to the multi-class endoscopic images and promote to build new approaches that could reliably be used in clinics. We report the performance of 21 participating teams over a  period of three consecutive years and provide a  detailed analysis of the methods used by the participants, highlighting the challenges and shortcomings of the current approaches and dissect their credibility for the use in clinical settings.  Our analysis revealed that the participants achieved an improvement on maximum  Mathew correlation coefficient  (MCC)  from  82.68%  in  2017  to  93.98%  in  2018  and 95.20% in 2019 challenges, and a significant increase in computational speed over consecutive years.

Colonoscopy is considered the gold standard for detection of colorectal cancer and its precursors. Existing examination methods are, however, hampered by high overall miss-rate, and many abnormalities are left undetected. Computer-Aided Diagnosis systems based on advanced machine learning algorithms are touted as a game-changer that can identify regions in the colon overlooked by the physicians during endoscopic examinations, and help detect and characterize lesions. In previous work, we have proposed the ResUNet++ architecture and demonstrated that it produces more efficient results compared with its counterparts U-Net and ResUNet. In this paper, we demonstrate that further improvements to the overall prediction performance of the ResUNet++ architecture can be achieved by using Conditional Random Field (CRF) and Test-Time Augmentation (TTA). We have performed extensive evaluations and validated the improvements using six publicly available datasets: Kvasir-SEG, CVC-ClinicDB, CVC-ColonDB, ETIS-Larib PolypDB, ASU-Mayo Clinic Colonoscopy Video Database, and CVC-VideoClinicDB. Moreover, we compare our proposed architecture and resulting model with other State-of-the-art methods. To explore the generalization capability of ResUNet++ on different publicly available polyp datasets, so that it could be used in a real-world setting, we performed an extensive cross-dataset evaluation. The experimental results show that applying CRF andTTA improves the performance on various polyp segmentation datasets both on the same dataset and cross-dataset. To check the model’s performance on difficult to detect polyps, we selected, with the help of an expert gastroenterologist,196sessile or flat polyps that are less than ten millimeters in size. This additional data has been made available as a subset of Kvasir-SEG. Our approaches showed good results for flat or sessile and smaller polyps, which are known to be one of the major reasons for high polyp miss-rates. This is one of the significant strengths of our work and indicates that our methods should be investigated further for use in clinical practice.